Zydus -Saroglitazar -FDA fast track designation for PBCDrug firm Zydus Cadila on Wednesday said it has received Fast Track Designation from the US health regulator for its investigational drug candidate Saroglitazar Mg, indicated for the treatment of
CymaBay -Seladelpar Phase 3 Enhance Study shows positive resultsAt AASLD 2020 virtual liver conference, Dr. Gideon Hirschfield presented promising Phase 3 results for Seladelpar a treatment for patients with PBC. Positive outcomes included: 78% of those in the
Escient – upcoming clinical trial for PBC itchThere is a new clinical trial aimed at PBC pruritus. While the study is currently in New Zealand and Australia, there are plans to expand the trial to PBC patients
Linerixibat (GSK2330672) Phase 2b ResultsLinerixibat (GSK2330672), a drug that is being developed for PBC patients who experience itchiness, has recently published Phase 2b results. This is promising news for patients who are suffering from
Real-World Effectiveness of Obeticholic Acid – new study
Obeticholic Acid was approved in Canada in May 2017, this study describes its effectiveness in two Canadian centers. Read more.
CymaBay – Seladelpar – re-initiating Phase 3 clinical trial for PBCOn November 25, 2019, CymaBay halted all clinical trials of seladelpar after atypical histologic findings with no clinical or laboratory correlates were identified at the planned end-of treatment biopsy review
PBC Patient Guidelines
This year the PBC Network created a 36 page booklet “PBC – Living With Your Diagnosis” . The Canadian PBC Society participated in the final review of this comprehensive patient guideline and is now a proud member of the PBC Network. Read the guidelines here.