Clinical trials

Participating in a clinical trial or taking part in a research study can be a very rewarding way to get involved in helping to ensure all patients have access to safe and effective treatments.

There are many clinical trials taking place in Canada (list updated April 2022).  If you are interested in participating in any of these trials, ask your specialist to find out if you would benefit from and/or qualify for any of these clinical trials.

  • SELADELPAR (CymaBay) – Phase 3 trial enrolling:  Toronto, Ontario (2 sites), London Ontario, Ottawa Ontario. Check back for sites in Canada
  • ELAFIBRANOR (Genfit) – Phase 3 trial currently enrolling: Vancouver, Calgary, Winnipeg & Montreal  Check back for sites in Canada
  • LINERIXIBAT (GSK) – Phase 3 long term study currently enrolling: Toronto and Ottawa, Ontario. Check back for more sites in Canada
  • OCALIVA (Intercept)  – Phase 4 COBALT long term study, currently enrolling: Toronto, London, Calgary, Edmonton, Winnipeg, Montreal
  • EP547 (Escient) – Phase 2 trial –  not yet enrolling.
  • VOLIXIBAT (Mirum) – Phase 2 trial now enrolling in Florida, California & Mississippi
  • SETANAXIB (Calliditas) – Phase 2b/ trial enrolling sites in Canada: In Ontario:  Toronto, North York, London & North Bay.  In Alberta:  Calgary.  check back for more sites in Canada


  • SAROGLITAZER (Zydus) – Phase 2 completed
  • EDP-305 (Enanta) – terminated
  • ABATACEPT (Bristol-Myers Squibb) – terminated
  • CILOFEXOR (Gilead) – terminated
  • ETRASIMOD (Arena) – terminated
  • TROPIFEXOR (Novartis) – terminated

or use the CLINICAL TRIAL search tool below: